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CURRICULUM VITAE

Dr. Wasim Ahmed

Postal Address: 73. B / II, P.E.C.H.S., Karachi-75400. PAKISTAN
Tel. 9221-4556580 / 9221-8121526

 Personal Data

Date of Birth: December 24, 1961
Marital Status: Married
Number of Children: Three
Nationality: Pakistani

 Academic Career

 B. Sc, (Biochemistry, Microbiology, Chemistry), 1st Div., 1982
 M. Sc (Biochemistry), 1st, Div, 1985
 Ph. D, Organic Chemistry, 1993

 Doctoral & Postdoctoral Experience

 Doctoral work completed at H.E.J. Research Institute of Chemistry, University of Karachi.
 Major Field of research: isolation and characterization of natural products such as terpenoids, steroids, steroidal glycosides and pyrrolizidine alkaloids.
 Developed knowledge of chromatographic techniques such as MPLC, Flash, Centrifugal and HPLC etc.
 Strong background in modern spectroscopic techniques as 1D-, & 2D-NMR, HRMS, etc.
 Worked as a Postdoctoral Fellow in Germany & H.E.J. Res. Instt. of Chemistry.
 Published 23 Research Publications in International and National journals of chemistry.

 Awards / Scholarships / Certificates

 Certificate of Merit in B.Sc.
 DAAD Scholarship (Germany).
 Certificate in training course of Abbott Manager Program.
 Shield on contribution in a CGMP Training Program (presentation on Analytical Method Validation).
 International Certificate in contributing in a project of Environment Health and Safety.
(EHS)

 Industrial Experience
(1995-To-date)

 Joined Abbott as Senior Chemist in Quality Assurance Department.
 After two years promoted to Assistant Manager Chemical. (Group Leader of HPLC section):
• Planning and organizing the workload, trouble-shooting and testing of online products
 Later, promoted in Pakistan Technical Center as Manager, Product Development.
 Current position: Manager, Chemical.

• Skills and experience in Instruments handling and Testing

 UV Spectrophotometer, FTIR (IRDM), Karl Fischer Autotitrator, Ordinary Dissolution Apparatus, Auto dissolution Apparatus, Atomic Absorption and software controlled HPLCs.
 Testing of on-line products, raw materials and Stability Testing
 Documentation of Technical Packages (Method Change, Formula Change and Process Change)

• Experience in Computers / Soft wares

 IBM, IBM Compatibles, Apple Macintosh
 MS-WORD, LOTUS 1-2-3, AmiPro, WordPro, Windows-98, Windows XP, ChemDraw, ChemWin, PowerPoint, Excel, Lotus Notes, etc.
 Chromatographic Data Systems: Class 10Avp, LC10A, CSW32, TC4

• Experience in Method Validation

 Developed several analytical methods of finished products on HPLC.
 Method writing, report writing and preparation of Validation Packages

• Additional Experience

 Bio-Equivalence Studies on Sparfloxacin
 TPM Manufacturing of Antiobiotics at Unipharma (Damascus)
 Lead the several Technical Projects, e.g:
o Deletion of Methylene Chloride from the Coating Solution.
o Reformulation of Cough and Cold preparations by replacing Phenylpropanolamine with Pseudoephedrine
o Direct compression of vitamin tablet formulations

LIST OF PUBLICATIONS

A. PAPERS, COMMUNICATIONS & LETTERS

1. Two triterpenes from the leaves of Ficus carica, W. Ahmed, A.Q. Khan and A. Malik, Planta Medica, 54, 481 (1988).

2. Plumerinine---A novel Lupin-type alkaloid from Plumeria rubra, S.N.H. Kazmi, Z. Ahmed, W. Ahmed and A. Malik, Heterocycles, 29, 1901 (1989).

3. Triterpenes from the leaves of Ficus carica, W. Ahmed, A.Q. Khan and A. Malik, Fitoterapia, LXI, 373 (1990).

4. The Pyrrolizidine alkaloids from Senecio racemosus, W. Ahmed, Z. Ahmed, F. Ergun, B. Sener and A. Malik, Heterocycles, 32, 1729 (1991).

5. Stigmasteryl galactoside from Rhynchosia minima, W. Ahmed, Z. Ahmed and A. Malik, Phytochemistry, 31, 4038 (1992).

6. Pyrrolizidine and seco-pyrrolizidine alkaloids from S. Racemosus, W. Ahmed, A.Q. Khan, F. Ergun, B. Sener and A. Malik, J. Nat. Prod., 55, 1764, (1992).

7. Racemodine--A pyrrolizidine alkaloid from S. Racemosus, W. Ahmed, A.Q. Khan, F. Ergun, B. Sener and A. Malik, Phytochemistry, 32, 224 (1993).

8. A new pyrrolizidine alkaloid from S. Racemosus and revised structure of Racemonine, W. Ahmed, A.Q. Khan, F. Ergun, B. Sener and A. Malik, Fitoterapia, LXIV, 361 (1993).

9. Some neutral constituents of S. Racemosus, W. Ahmed, Z. Ahmed and A. Malik, Fitoterapia, LXV, 184 (1994).

10. A lupene-type triterpene from Mimusops elengi, N. Jahan, W. Ahmed and A. Malik, Phytochemistry, 39, 255, (1995).

11. Steroidal glycosides from M. elengi, N. Jahan, W. Ahmed and A. Malik, J. Nat. Prod., 58, 1244 (1995).

12. A method for the synthesis of C-(2-deoxy-b-glycosyl) arenes, A.T. Khan, W. Ahmed and R.R. Schmidt, Carbohydr. Res.,

13. Flourine and enzymes in organic chemistry, M.S. Ali and W. Ahmed, Hamdard Medicus, XXXVIII (3), 35 (1995).

14. An antimicrobial ecdysone from Asparagus dumosus, V.U. Ahmad, S.M.
Khaliq-uz-Zaman, M.S. Ali, S. Perveen and W. Ahmed, Fitoterapia, LXVI, 88 (1996).

15. A new sterol from M. Elengi, N. Jahan, W. Ahmed and A. Malik,
Fitoterapia, LXVI, 91 (1996).

B. REVIEW ARTICLES

1. Phytochemical studies on the constituents of R. Minima, W. Ahmed and
A. Malik, Hamdard Medicus, XXXVI (2), 26 (1993).

2. Phytochemical studies on the species of the genus Abutilon, Z. Ahmed, S.N.H. Kazmi, W. Ahmed and A. Malik, Hamdard Medicus, XXXVI (3), 28 (1993).

3. Phytochemistry of the genus Saponaria, S.N.H. Kazmi, Z. Ahmed, W. Ahmed and A. Malik, J. Chem. Soc. Pak., 15, 271 (1993).

4. Phytochemical studies on the constituents of F. Carica (FIG), W. Ahmed and A. Malik, Hamdard Medicus, XXXVII (2), 30 (1994).

5. The pyrrolizidine alkaloid-content of the genus Senecio, W. Ahmed, Z. Ahmed, S.N.H. Kazmi and A. Malik, J. Chem. Soc.Pak., 16, 64 (1994).

6. Phytochemistry of the genus Mimusops, N. Jahan, W. Ahmed and A. Malik, J. Chem. Soc. Pak., (In press).

7. Phytochemistry of the genus Asparagus, V.U. Ahmad, S.M. Khaliq-uz-Zaman, W. Ahmed, M.S. Ali, A. Malik, I. Azhar, J. Chem. Soc.Pak., 39 (2), 27 (1996).

C. PROCEDINGS

1. Epoxy sugars as intermediates in carbohdrates syntheses, A. Malik, F. Zaman, N. Akhter, N. Naz, A. Fatima, W. Ahmed, N. Afza, A. Majeed, N. Rasool, S.N.H. Kazmi and Z. Ahmed, in "Advances in Natural Products Chemistry", Ed. Atta-ur-Rahman, Harward Academic Publisher, Netherlands, p. 121 (1992).

2. Two new steroidal glycosides and lupene-type triterpene from Mimusops elengi, N. Jahan, W. Ahmed and A. Malik, in "Procedings of the 5th International Chemistry Conference, (In Press).